Description
MARY & MAY Spicule Retinol PDRN Cream is a targeted moisturizer designed to revitalize dull, sagging, or aging skin. This advanced formula combines 2,000 ppm spicules, 1,000 ppm retinol, 2% panthenol, and CICA PDRN to deliver visible results while minimizing irritation. Ideal for those seeking intensive care for enlarged pores, loss of elasticity, or rough skin texture.
Why This One
- Contains 2,000 ppm spicules and 1,000 ppm retinol for intensive skin renewal, providing a potent concentration for visible improvement.
- Infused with 2% panthenol and CICA PDRN to soothe and reinforce the skin barrier, making it suitable for sensitive or easily irritated skin.
- Made in Korea, ensuring high manufacturing standards and quality control.
Key Features
- Fragrance-free formula for minimized risk of irritation.
- Spicule technology enhances absorption of active ingredients deep into the skin.
- 4X low-irritation complex with panthenol, hyaluronic acid, ceramide NP, and allantoin to calm, hydrate, and protect.
- Supports collagen barrier strength with plant-derived CICA PDRN.
- Suitable for use on the entire face, including areas prone to enlarged pores and loss of firmness.
How to Use
- After cleansing, apply a thin, even layer to clean skin as the first step of your routine.
Avoid sensitive areas such as around the eyes and areas prone to irritation. - Gently spread along the skin texture, then lightly press with your palms for absorption.
Ensure even application without excessive rubbing. - For first-time use, apply 2–3 times per week in the evening, gradually increasing frequency. If no irritation occurs, daily use is possible.
In the morning, always use sunscreen with SPF 30 or higher. - Follow with a moisturizing cream or soothing care product, as retinol may cause dryness.
Key Ingredients
- Spicule (2,000 ppm): Enhances delivery of actives deep into the skin.
- Retinol (1,000 ppm): Promotes skin renewal and improves texture.
- Panthenol (2%): Soothes and hydrates.
- CICA PDRN: Plant-derived, supports barrier and calms irritation.
- Hyaluronic Acid: Provides moisture retention.
- Ceramide NP: Strengthens the skin barrier.
- Allantoin: Calms and protects sensitive skin.
Specifications
| Volume | 15g |
|---|---|
| Country of Origin | Korea |
| Fragrance | Fragrance-Free |
Cautions
- Initial use may cause tingling, warmth, or redness; these are temporary and vary by skin type.
- If persistent discomfort, redness, or irritation occurs, discontinue use and consult a dermatologist.
- Do not use on compromised skin (post-procedure, laser, peeling, waxing) until fully healed.
- Avoid use with devices such as LED masks or high-frequency tools at the same time; ensure skin is calm before device use.
- Always use sunscreen during the day when using retinol products.
- Avoid contact with eyes and areas prone to irritation.

















