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Evolution history of IOPE’s retinol

Our research to stabilize retinol began in 1994. We have applied for 25 patents in Korea (registered 20) and 22 overseas patents (registered 14), published 10 SCI entries, presented at 17 international conferences, won six external awards, evaluated 500 skin-friendly ingredients, and reported 67 skin-friendliness evaluations. IOPE now proposes the 10th generation of its retinol.

레티놀 엑스퍼트 0.1%, 0.3% 관련 동영상 보기
하단 텍스트 참조

Can cosmetics really smooth out wrinkles?
It is possible with IOPE Retinol Expert!
In just 2 weeks, even thick wrinkles!

New content found at the end of professional research

We have consistently upgraded the retinol stabilization technology since 1997 and discovered high-content retinol to take intensive care of wrinkles.

Keeping the effect until the last drop

The effect is maintained until the very last drop of this product through a three-stage oxygen barrier system that prevents oxidation of retinol by light and air.

Definite wrinkle care effect shown in just two weeks

This product offers a definite wrinkle care effect in the three major anti-aging categories (wrinkle, firmness, density) in just two weeks.

하단 텍스트 참조Forehead wrinkles -11.0%
Wrinkles under the eyes -15.4%
Pore area -28.0%
Nasolabial fold -26.1%
Neck Wrinkles -5.1%

Only 2 weeks!
From thick wrinkles to 'more' thick wrinkles
Step-by-step improvement effect

Surprising effects in three major
anti-aging categories: Wrinkle, firmness, density

Wrinkles below the eyes
15.4%  Reduced wrinkles below the eyes
6.3Increased firmness below the eyes
26.8Increased density below the eyes

Nasolabial folds

26.1Reduced nasolabial folds
7.5Increased nasolabial firmness
25.2Increased nasolabial density

· Period: September 16 ~ October 17, 2019/ Agency: P&K Skin Research Center / Subjects: Adult women aged 40-59 years, N=40
· These images correspond to the top 5 subjects.
· Effects can vary among individuals.

 * Retinol Expert 0.2%
2021.01.25-02.24 / PNK Skin Clinical Research Center Co., Ltd. / Adult female aged 40-59 (N=31)
This image corresponds to the Top 1 improvement rate. Efficacy effects may vary from person to person.


    Forehead wrinkles

    11.0Reduced forehead wrinkles

    · Period: September 17 ~ October 18, 2019/ Agency: P&K Skin Research Center / Subjects: Adult women aged 40-59 years, N=39
    · These images correspond to the top 5 subjects.
    · Effects can vary among individuals.
    · Improvement of loose pores is a temporary effect.

    Surprising changes in the skin
    experience in just two weeks

    Four items improved in just two weeks
    Wrinkles below the eyes & nasolabial folds, firmness, density, moisturizing

    Five items improved in just four weeks
    Including translucency` 

    Only 2 weeks!
    from visible pores 
    Even sagging pores like wrinkles!
    Step-by-step improvement effect


    Number of pores
    -10.9% reduction

    * Retinol Expert 0.1%
    2020.08.26-09.25 / PNK Skin Clinical Research Center Co., Ltd. / Adult female aged 40-59 (N=39)
    This image corresponds to the top 3 improvement rate. Efficacy effects may vary from person to person.

    Pore area
    -28% reduction

    * Retinol Expert 0.2%
    2021.01.25-02.24 / PNK Skin Clinical Research Center Co., Ltd. / Adult female aged 40-59 (N=31)
    This image corresponds to the Top 1 improvement rate. Efficacy effects may vary from person to person.

    Loose pores

    2.3Reduced loose pores

      * Retinol Expert 0.3%
      2019.09.16-10.17 / PNK Skin Clinical Research Center Co., Ltd. / Adult female aged 40 to 59 (N=40)
      This image corresponds to the Top 1 improvement rate. Efficacy effects may vary from person to person.



      What is Retinol?
      Wrinkle improvement, the standard of anti-aging ingredients!
      Pure vitamin A, an anti-aging ingredient with a long history and proven efficacy as mentioned by the ancient Hippocrates

      Retinol stimulates collagen production and skin turnover!
      wrinkle improvement
      Improvement of pores/skin texture
      luster improvement

        Anti-wrinkle functional ingredient recognized by the Ministry of Food and Drug Safety of Korea
        vitamin A series

        Retinyl palmitate (=retinol derivative): Wrinkle improvement function recognized
        Retinol: Wrinkle improvement function recognized
        Retinoic acid: Not available as a cosmetic ingredient

        However, it is very difficult to develop ingredient stabilization technology, so there are only a few brands, including IOPE, that have been recognized for their wrinkle-improving functionality with retinol.

        Retinol, an wrinkle-improving functional ingredient approved by the Ministry of Food and Drug Safety
        27 years of reliable retinol research by IOPE

        1994 Started research on retinol
        1997 First-generation retinol, retinol 2500 launched

        “It was equivalent to two or more apartments in Seoul in the 1990s.
        I put my money into research on retinol.”
        “In 1997, when IOPE Wrinkle Improvement Essence was released,
        We have prepared a turning point in the domestic anti-aging cosmetics market.”
        “It was a product recognized by customers, selling KRW 30 billion within 5 months of its launch”

        2020 10th generation Retinol, Retinol Expert launched

        하단 텍스트 참조

        • 1997 1st Generation Retinol 2500 stabilization of pure retinol for the first time in Korea
        • 1998 2nd Generation Retinol 2500 Intensive Super Wide Liquid Crystaline (SWLC) technology that improves stability of retinol enhances skin absorption and efficacy
        • 3rd Generation Retinol Innovation in 2002 Improved skin affinity with LASS (Liquid-Crystal Association Stabilization System) technology, a retinol stabilization method that was originally developed
        • 2005 4th Generation Retinol TX RETINOTOX™, a combination of retinol and plant peptides
        • 2009 5th Generation Retinol NX Deep Wrinkle Corrector Care for deep wrinkles as well as invisible latent wrinkles
        • 2011 6th Generation Retinol TX Intensive Multi-wrinkle improvement effect with upgraded Retinotox™
        • In 2012, 7th Generation Retinol Age Corrector Retinogenic™ takes care of the five major signs of skin aging.
        • 2015 8th Generation Bio Retinol Bio-Retinogenic™ turns on the activation switch of skin collagen to improve nasolabial folds
        • 2017 9th Generation Age Corrector R.2500™ intensively strengthens the skin collagen spring to improve nasolabial folds and wrinkles under the eyes
        • A new content of 0.1% and 0.3% found at the end of the 2020 10th Generation Retinol Expert research, a definite wrinkle improvement effect

        아이오페 레티놀 연구 신문자료 [피부노화지연 '레티놀'상품화 성공], [피부노화 방지 기능 강화], [4년 연구끝에 상품화 성공], [이달부터 아이오페 레티놀 2500 발매… 업계 큰 관심]

        With 27 years of professional research, IOPE's retinol technology is recognized worldwide.
        • 25 Korean patent applications *20 registrations.
        • 500 skin-friendly ingredients.
        • 22 overseas patent applications *14 registered cases.
        • 67 skin affinity assessment reports.
        • SCI thesis presentation 10 times.
        • 6 awards.
        • 18 international conference announcements.

          아이오페 레티놀 익스퍼트 0.1%

          IOPE Retinol, proven by numerous customers and history
          We have been together for a long time for young skin of women.

          I've been using retinol since my late 20s, and even after I'm in my 50s, there are almost no fine lines.
          I know people look at me and think I'm in my 40s.
          I think the new retinol is even more amazing.
          As soon as I applied it the first day, my skin felt tighter the next morning.


          IOPE ONLY!
          For 4 years, I have been studying the skin of customers who use retinol.
          Will tolerance develop if used for a long time?
          Will irritation get worse if I use it for a long time?
          Does using it really improve wrinkles?

          You can trust and write!
          Even at 4 years older, with tighter skin!

          53 year old skin enlargement --> 57 year old skin enlargement
          2012.12.09~2016.12.09 / Adult female 40-53 years old (N=52) / Amorepacific Research Institute
          As an image corresponding to Top.1, there may be individual differences in efficacy and effectiveness.

          IOPE Retinol Expert, which is better the more you use it

          I want to know that!
          The reason IOPE Retinol Expert is special.
          Retinol is susceptible to light, heat, and oxygen, making it difficult to stabilize!

          Retinol that gets destroyed and reduced over time!

          But IOPE did that difficult thing!

          Stabilize pure retinol
          Effect even faster!
          strong for a long time!

          CubeCell System™ developed through 27 years of professional research
          A new technology that prevents the destruction of retinol without capsule coating!

          Because it is not coated with capsules, it absorbs quickly and protects the powerful pure retinol with antioxidants to prevent the destruction of retinol.

          Existing retinol technology that is easy to destroy --> IOPE cube cell system™

          Protects retinol to the last drop

          Retinol is rapidly destroyed when exposed to oxygen, light, and heat during use, and the fate of retinol depends on the container!

          It's hard to stop the destruction of retinol with ordinary containers!

          IOPE's unique 3-layer blocking container developed exclusively for retinol!

          1 Triple aluminum tube that blocks the transmission of oxygen and light
          2 Sealing responsible for airtightness before opening
          3 Air shutoff valve to prevent oxygen ingress during use

            Check it out when choosing retinol cosmetics!

            1. Whether it has been recognized as a functional cosmetic for wrinkle improvement with ‘retinol ingredient’!

            There are many cases where wrinkle-improving functionality is recognized with ingredients other than retinol (adenosine, etc.)?!
            IOPE Expert, recognized for its wrinkle-improving function with ‘retinol ingredient’
            = Recognized that retinol is well preserved and has a complete anti-wrinkle effect!

            IOPE Retinol Expert Product Functional Cosmetics Review Excluded Item Report, retinol raw material in 100 grams of this product is recognized by the Ministry of Food and Drug Safety PASS

            Like retinol cosmetics, ‘real retinol’ has been recognized for its anti-wrinkle function by the Ministry of Food and Drug Safety as ‘retinol ingredient’

            2. Is it a super high content of pure retinol?

            Skin customized content
            0.1%, 0.2%, 0.3% Lineup

            IOPE proposes customized content with high efficacy satisfaction through professional research for more than 27 years!

            4 times the basic retinol content* approved by the Ministry of Food and Drug Safety for wrinkle improvement (based on 0.3%)
            Pure retinol super high content
            IOPE Retinol Expert!
            * Wrinkle improvement functional notice content

            Contents announced by the Ministry of Food and Drug Safety for wrinkle improvement

            Moist retinol essence that adheres well to wrinkles

            No push or stickiness!

            Retinol Expert Selection Guide by Contents
            2 weeks
            Customized care for each aging stage and use situation!

            0.1% ALL-DAY USE
            0.2% POWER USE
            0.3% NIGHT RESET

            IOPE Retinol Expert Aging Steps and Usage Conditions Guide Table
            Wrinkle troublesSTEP 1

            When wrinkles in thin areas of the skin are a concern
            (eye area, nasolabial folds, etc.)

            STEP 2

            When makeup gets caught in the 'more' thick wrinkles

            STEP 3

            When you are concerned about thick wrinkles in areas with thick skin
            (Forehead wrinkles, etc.)

            Pore troublesSTEP 1

            When the skin texture looks bad due to the large number of visible pores

            STEP 2

            When the pores are enlarged due to a sharp decrease in elasticity

            STEP 3

            When pores are stretched in the direction of gravity and are just before wrinkles

            Skin type

            Recommended for Beginners to Retinol
            Thin skin
            Above skin sensitivity

            Retinol Intermediate Recommendation
            Normal skin
            Skin sensitivity

            Retinol Super High Recommended
            Thick skin
            Under skin sensitivity

            How to use

            All Day Retinol Rubber
            Everyday, daytime, when you want to apply it all over your face

            Power Retinol Users
            When you want to apply it every day to the areas of deep wrinkles

            Night reset user
            When you need a clear effect with only intensive care once a day, at night

            The more 'professional' prescription, the more things to follow, but the effect is clear.

            How to Open Bottle

            • STEP 01

              Grab the ring long to remove it.
              (If the ring cannot be removed easily, slightly turn the cap to loosen it.)

            • STEP 02

              Turn the cap counterclockwise until the end to bore the inside and attach the inner cap.

            • STEP 03

              Turn in the opposite direction to open the cap.
              ※ After opening for the first time, open and close the cap lightly. 


            HOW TO USE

            Make sure to read and understand the user guide in order to enjoy the powerful effects of retinol.

            • After using skin lotion essence/serum, aging such as wrinkles
              Apply an appropriate amount around the area of concern.
              (After skin adaptation, it can be used all over the face.)
            • At the last step, add cream to finish. 
              Even better.
            • Wear sunscreen when going out while using retinol. 
              Please use it.
              (※ Retinol absorbed overnight remains on the skin, so use retinol during the day.
              We recommend that you use sunscreen even if you don't apply it.)
            • If you are using it for the first time, please read the skin adaptation guide. 

            Skin adaptation guide

            Skin adaptation period (1~2 weeks of first use)
            Recommended for use every other day/evening

            • Apply a small amount to each area of concern.
              Less than half of the usual amount of essence used)
            • Depending on individual differences, the adaptation period can be shortened or increased.
              Please take the adjustment period until there is no skin discomfort.

            After skin adaptation
            Daily use / morning and evening use,
            (Recommended to use continuously every other day in 0.3% of cases)

            • Apply an appropriate amount to the entire face.
            • Experience the various effects of retinol by gradually increasing the dose and area used.

            Use cycle

            0.1%, 0.2%
            Use every other day for 2 weeks, daily after 2 weeks

            아이오페 레티놀 포 링클 0.1% 2주간은 격일사용, 2주 이후 매일 사용

            Continuous use every other day

            아이오페 레티놀 포 링클 0.3% 지속적으로 격일 사용
            • Please use sunscreen during the day while using the product.
            • Since retinol is weak against light and heat, it is recommended to use it at night, but it is okay to use it during the day after getting used to it.
              (Please take extra care with sunscreen!)
            • Avoid physical and chemical scrubs/peeling products, and refrain from using cosmetic devices or procedures in parallel.
            • Before using retinol, carefully apply skin lotion. (When managing neck wrinkles, apply skin lotion to the neck before use)

            REAL User Reviews

            I use it intensively on the nasolabial folds.
            No, it feels like the pores are getting smaller?!
            It has changed that makeup was caught in the wrinkles.
            Especially the nasolabial folds! The wrinkles around the bridge of the nose are noticeably improved.

            I have nothing to say. This is my third purchase and I am using it.
            You can apply it at night and look in the mirror in the morning to be satisfied.
            It is the only product. Noticeable wrinkles around the eyes and nasolabial folds
            I was worried because it disappeared and under my eyes went dark, but it was corrected
            I think I will continue to repurchase. you should try it out
            same. I hope everyone is as happy as me.
            It's really a real recommendation.


              • 30's aclsq****
                When I first started applying retinol, I was surprised every morning.
                I feel like my skin is becoming luxurious day by day, so I look in the mirror first as soon as I open my eyes in the morning. I was greedy from the first time I applied it, so I applied it all over my face like an essence~^^

                My skin was dry! pores! Figure 11 wrinkles?!
                It was always stressful every time I looked in the mirror, but now others recognize me first~^^

                It's been about 5 months since I applied retinol, but now I go with confidence as if my skin was originally good~^^

                I bought it at 80,000 won and saw the effect of 8 million won~^^
                Retinol Alabou~♥

              • 40's jjun****
                I have sensitive skin, so I haven't tried it yet, but I was concerned about the wrinkles on my neck, so I started it first.
                It's been a week, is this a true story?
                I can see with my own eyes that the deep wrinkles on the neck have softened.

                It's no joke, it's a little red and itchy the first time I applied it, but after the second time it's okay. I'm going to try to get rid of the wrinkles on my neck.

              • 50s 0102353****
                It was my first time using this product, but I was concerned about the wrinkles around the eyes and neck, but every time I use it, when I wake up in the morning, I feel really good because I feel sticky and firm on my face.

                The next step is to purchase the product later. I want to recommend it to everyone around me.

              Wrinkles separately, properly, with retinol.
              You can change the future of wrinkles


              Purified water, caprylic/capric triglyceride, propanediol, glycerin, dimethicone, tocopherol, tocopheryl acetate, trehalose, panthenol, shea butter, soja bean oil, ammonium acryloyldimethyltaurate/VP copolymer, glyceryl polymethacrylate, polysilicone-11, hydrogenated lecithin, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, polyglyceryl-10 stearate, rice bran wax, cetearyl alcohol, carbomer, fragrance, sodium sulfite, tromethamine, retinol, allantoin, glyceryl caprylate, mannitol, glyceryl stearate, disodium EDTA, ethylhexylglycerin, stearic acid, polyglyceryl-3 methylglucose distearate, palmitic acid, sorbitan isostearate, BHT, myristic acid, lauric acid, acetyl tetrapeptide-11, ascorbic acid, meadowfoam seed oil, ethyl ascorbyl ether, sodium ascorbate, glutathione, sodium hyaluronate, 1,2-hexanediol, hydrolyzed hyaluronic acid, sodium hyaluronate crosspolymer, hyaluronic acid, sodium acetylated hyaluronate




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